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CDH5 — MAPK12
Text-mined interactions from Literome
Nwariaku et al., Shock 2002
:
Inhibition of p38 but not ERK
MAPK significantly
reduced the effect of TNFalpha on endothelial permeability and cell-surface
VE cadherin expression
Ordóñez-Morán et al., J Cell Biol 2008
(Colonic Neoplasms) :
As shown by the use of chemical inhibitors, dominant negative mutants and small interfering RNA, RhoA-ROCK, and
p38MAPK-MSK1 activation is
necessary for the induction of
CDH1/E-cadherin , CYP24, and other genes and of an adhesive phenotype by 1,25 ( OH ) ( 2 ) D ( 3 )
Kolosova et al., J Cell Physiol 2011
:
However, neither Smad2/3 nor p38
MAPK were
required for the down-regulation of
E-cadherin , yet p38 MAPK was associated with fibronectin up-regulation