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MYLIP — PDGFB

Text-mined interactions from Literome

Maurer et al., Arthritis Rheum 2010 (Scleroderma, Systemic) : TGFbeta, PDGF-B , or IL-4 reduced the levels of miR-29a in normal fibroblasts to those seen in SSc fibroblasts
Shao et al., Nucleic Acids Res 2011 (Glioblastoma...) : The two PDGF ligands AA and BB affect expression of several miRs in ligand-specific manner ; the most robust changes consisting of let-7d repression by PDGF-AA and miR-146b induction by PDGF-BB ... Induction of miR-146b by PDGF-BB is modulated via MAPK dependent induction of c-fos
Costa et al., Hum Mol Genet 2012 (Disease Models, Animal...) : PDGF-B mediated downregulation of miR-21 : new insights into PDGF signaling in glioblastoma ... Retrovirally mediated overexpression of PDGF-B in U87 human GBM cells or their prolonged exposure, as well as that of F98 rat glioma cells to this ligand, resulted in decreased miR-21 and miR-128 levels, which was associated with increased cell proliferation
Põlajeva et al., BMC cancer 2012 (Glioma) : Interestingly, in normal fibroblasts the expression of miR-21 was induced by PDGF-BB , and inhibition of PDGF signaling in mouse glioma primary cultures resulted in suppression of miR-21 suggesting that miR-21 is indeed regulated by PDGF signaling
Hu et al., Cell death & disease 2012 (Disease Models, Animal) : Furthermore, it was shown that PDGF-B was a target for miR-29b as evidenced by the fact that binding of miR-29 to the 3'-untranslated region of PDGF-B mRNA resulted in its translational repression in SH-SY5Y cells