Matta et al., J Biol Chem 2007
:
Furthermore, endogenously expressed TRAF2 and TRAF3 do not interact with K13 and play no role in K13 induced NF-kappaB activation or its interaction with the IKK complex Matta et al., Oncogene 2008
(Sarcoma, Kaposi) :
K13 interacts with and activates the nuclear IKK complex , and binds to the IkappaBalpha promoter
Matta et al., PloS one 2012
(Chronic Disease...) :
On the other hand, NEMO was required for interaction of K13 with IKK1/IKKa and IKK2/IKKß, which resulted in their activation by `` T Loop '' phosphorylation