Gene interactions and pathways from curated databases and text-mining

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CTNNB1 — PVRL1

Pathways - manually collected, often from reviews:

  • NCI Pathway Database Nectin adhesion pathway: nectin-1(dimer)/I-afadin/I-afadin/nectin-1(dimer)/I-afadin/I-afadin complex (PVRL1-MLLT4) → E-cadherin/beta catenin/alpha catenin complex (CDH1-CTNNB1-CTNNA1) (translocation, activates)
    Tachibana et al., J Cell Biol 2000
    Evidence: assay, physical interaction