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ID1 — TGFB1
Text-mined interactions from Literome
Damdinsuren et al., Oncol Rep 2006
(Carcinoma, Hepatocellular...) :
Induction by TGF-beta1 dose-dependently suppressed Id1 expression in HuH7 cells ; 1 ng/ml
TGF-beta1 inhibited
Id1 by 84.0 and 78.6 % that of the untreated control at transcriptional and protein levels, respectively
Li et al., J Am Soc Nephrol 2007
:
Overexpression of ILK or inhibition of ILK activity had no effect on
Id1 induction by
TGF-beta1 , suggesting that Id1 and ILK have independent roles in epithelial dedifferentiation and EMT
Lin et al., Am J Pathol 2008
(Pulmonary Fibrosis) :
Dril1
enhanced activation of
TGF-beta(1) target genes, whereas
Id1 decreased expression of these same molecules
Liang et al., Cell Res 2009
:
During our study of the biological function of TGF-beta1, we found that
Id1 can be strongly
up-regulated by
TGF-beta1 in the human mammary gland epithelial cell line MCF10A ... Our results demonstrate that Smad3, but not Smad2, mediates
TGF-beta1 dependent early transcriptional
induction of
Id1