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ELMO3 — RAC3

Text-mined interactions from Literome

Brugnera et al., Nat Cell Biol 2002 : We can also detect a trimeric ELMO1 Dock180 Rac1 complex and ELMO augments the interaction between Dock180 and Rac
Lu et al., Methods Enzymol 2006 : The best characterized is the Rac activation by the Dock180-ELMO complex
Tosello-Trampont et al., Cell Death Differ 2007 : Although the role of ELMO : Dock180 in regulating Rac activation has been well defined, the function of CED-2/CrkII in this complex is less well understood
Komander et al., Mol Biol Cell 2008 : Significantly, although this does not affect DOCK180 GEF activity toward Rac in vivo, Rac signaling is impaired, implying additional roles for ELMO in mediating intracellular Rac signaling