Gene interactions and pathways from curated databases and text-mining

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CDKN2A — EPHB2

Text-mined interactions from Literome

Wen-Sheng et al., Oncogene 2003 (Carcinoma, Hepatocellular...) : These results suggested that activation of ERK together with its downstream transcriptional machinery mediated p15(INK4b) and p16(INK4a) expression that led to HepG2 growth inhibition
Han et al., J Biol Chem 2005 (Carcinoma, Hepatocellular...) : Hepatocyte growth factor induces redistribution of p21 ( CIP1 ) and p27 ( KIP1 ) through ERK dependent p16(INK4a) up-regulation, leading to cell cycle arrest at G1 in HepG2 hepatoma cells
Giles et al., Br J Dermatol 2012 (MAP Kinase Signaling System...) : We show that UVR induced ERK signalling, mediated by BRAF, regulates p16 ( CDKN2A ) expression at the transcriptional, and possibly translational level