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EPHB2 — IKBKB

Text-mined interactions from Literome

Mechtcheriakova et al., FASEB J 2001 (MAP Kinase Signaling System) : TNF-alpha mediated activation of MEK/ERK and EGR-1 can be blocked by adenoviral expression of a dominant negative mutant of IKK2 , whereas the VEGF signaling pathway is unaffected
Shan et al., Am J Physiol Lung Cell Mol Physiol 2006 (Asthma...) : Complementary studies further demonstrated that the ASM responses to LPS were associated with activation of the ERK1/2 and p38 MAPK signaling pathways, IKK mediated activation of NF-kappaB, and coupling of phosphorylated ERK1/2 with the p65 subunit of NF-kappaB
Huang et al., Biochem Pharmacol 2007 (Lung Neoplasms) : The SDF-1alpha mediated increases in IKK alpha/beta phosphorylation, p65 Ser ( 536 ) phosphorylation, and kappaB-luciferase activity were inhibited by PD98059 and ERK2 mutant
Chen et al., TheScientificWorldJournal 2010 : Blocking phosphorylation of ERK1/2 by MAPK inhibitors U0126 and PD98059, and inhibiting activation of NF-?B by IkappaB ( I?B ) kinase inhibitors wedelolactone or IMD-0354, abolished the DSP effects
Yang et al., Mol Cell Biol 2012 : Unexpectedly, TPL-2 promoted soluble TNF production independently of IKK induced p105 phosphorylation and its ability to activate ERK , which has important implications for the development of anti-inflammatory drugs targeting TPL-2
Slomiany et al., Inflammopharmacology 2013 : Induction in gastric mucosal prostaglandin and nitric oxide by Helicobacter pylori is dependent on MAPK/ERK mediated activation of IKK-ß and cPLA2 : modulatory effect of ghrelin
Lee et al., Proc Natl Acad Sci U S A 1998 : We have previously shown that mitogen activated protein kinase/ERK kinase kinase 1 ( MEKK1 ) can induce both this site-specific phosphorylation of IkappaB alpha at Ser-32 and Ser-36 in vivo and the activity of a high molecular weight IkappaB kinase complex in vitro