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IL10 — MTA3
Text-mined interactions from Literome
Moreno et al., Ann Neurol 2006
(Disease Models, Animal...) :
Indeed,
MTA suppressed the production of proinflammatory genes and cytokines ( interferon-gamma, tumor necrosis factor-alpha, and inducible nitric oxide synthase ) and
increased the production of antiinflammatory cytokines (
interleukin-10 )
Rezende et al., J Endod 2008
:
Although
MTA did not
affect the upregulated expression of
interleukin 10 , tumor necrosis factor alpha, or RANKL by Tm, it suppressed the proliferation of Pa- or Fn-Tm and inhibited their production of Th1- or Th2-signature cytokines
Li et al., Carcinogenesis 2012
(Cell Transformation, Neoplastic...) :
In these cells, SAMe and
MTA inhibited IL-6 induced
IL-10 expression ...
MTA also
inhibited IL-10 transcription and signal transducer and activator of transcription 3 activation