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MYOG — PI3

Text-mined interactions from Literome

Tureckova et al., J Biol Chem 2001 : Induction of myogenin by IGF-I and myotube formation were prevented by the phosphatidylinositol (PI) 3-kinase inhibitor, LY294002, even when included 2 days after growth factor addition, whereas expression of active PI 3-kinase could promote differentiation in the absence of IGF-I
Wilson et al., Mol Biol Cell 2004 : Inhibition of PI3-kinase did not prevent accumulation of muscle differentiation-specific proteins ( myogenin, troponin T, or myosin heavy chain ), did not block transcriptional activation of E-box containing muscle reporter genes by MyoD or myogenin , and did not inhibit the expression or function of endogenous MEF2C or MEF2D