Gene interactions and pathways from curated databases and text-mining

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NOX4 — SETD2

Text-mined interactions from Literome

Dong et al., Zhongguo Dang Dai Er Ke Za Zhi 2006 : To study the effect of NADPH oxidase on hypoxia-inducible factor (HIF)-1alpha and endothelin (ET)-1 expression in human umbilical endothelia cells ( HUVECs ) and its possible mechanism
Kim et al., Prostate 2011 (Neovascularization, Pathologic...) : Also, PKCd induced activation of NADPH oxidase increased the level of HIF-1a
Semenza et al., Adv Exp Med Biol 2012 : HIF-1 activates transcription of the Nox2 gene, encoding NADPH oxidase 2, which generates superoxide
Meng et al., PloS one 2012 : NADPH oxidase 4 mediates insulin stimulated HIF-1a and VEGF expression, and angiogenesis in vitro ... In this study we examined the role of NADPH oxidase subunit 4 (Nox4) in insulin stimulated HIF-1a and VEGF expression, and angiogenic responses in human microvascular endothelial cells ( HMVECs )