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EIF2AK2 — IL6

Text-mined interactions from Literome

Tanaka et al., Gene 2000 : Northern blot analysis showed efficient IFN-alpha induced accumulation of 2.4kb, 4.5kb and approx. 6kb Pkr transcripts, but neither IFN-gamma nor IL-6 induced detectable Pkr mRNA accumulation in L cells
Paludan et al., J Virol 2001 : This suggests a role for PKR in HSV induced IL-6 expression ... The results show that induction of IL-6 by HSV in leukocytes is dependent on PKR and cellular signaling through NF-kappaB and a p38 dependent pathway
Shi et al., J Nutr Biochem 2009 : These data suggest that DON induced IL-6 expression is CREB mediated and PKR dependent , and that requisite kinase activities for these pathways were suppressed in macrophages from mice fed DHA for an extended period
Lin et al., Cytokine 2010 : A role for protein kinase PKR in the mediation of Epstein-Barr virus latent membrane protein-1 induced IL-6 and IL-10 expression