Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
O/- complex ()
→
Complex of JUND-RB1
(increases, JUND/RB1 Activity)
Evidence: RB1&CEBPB^taof(CEBPB) Hypophosphorylated pRb binds c-Jun, JunD, and JunB (Nead et al., 1998). This enhances the binding of the Jun family members to c-Fos and stimulates transcriptional activation by the Fos:Jun complexes. A region (amino acids 612?657) in the B-pocket of pRb and a region in the C-pocket can independently bind c-Jun. The binding site in c-Jun is in the leucine zipper region.