Gene interactions and pathways from curated databases and text-mining

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JUND — RB1

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: O/- complex () → Complex of JUND-RB1 (increases, JUND/RB1 Activity)
    Evidence: RB1&CEBPB^taof(CEBPB) Hypophosphorylated pRb binds c-Jun, JunD, and JunB (Nead et al., 1998). This enhances the binding of the Jun family members to c-Fos and stimulates transcriptional activation by the Fos:Jun complexes. A region (amino acids 612?657) in the B-pocket of pRb and a region in the C-pocket can independently bind c-Jun. The binding site in c-Jun is in the leucine zipper region.