Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
ERBB2
→
PLCD4
(increases, ERBB2 Activity)
Leung et al., Molecular cancer 2004* Evidence: Overexpression of PLCdelta4 selectively activates protein kinase C-phi and upregulates the expression of epidermal growth factor receptors EGFR/erbB1 and HER2/erbB2, leading to constitutive activation of extracellular signal-regulated kinases 1 and 2 (ERK1/2) pathway in MCF-7 cells.