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STAT3 — TNFRSF1B

Text-mined interactions from Literome

Hamilton et al., Mol Cancer Res 2011 (Colonic Neoplasms) : Cytokine induction of tumor necrosis factor receptor 2 is mediated by STAT3 in colon cancer cells ... Constitutively active STAT3 was sufficient to induce TNFR2 expression ... Collectively, these studies show that IL-6- and TNFa induced TNFR2 expression in colon cancer cells is mediated primarily by STAT3 and provide evidence that TNFR2 may contribute to the tumor promoting roles of STAT3
Yamada et al., Hepatology 1998 : Lack of TNFR-2 had little effect on NF-kappaB and STAT3 binding, and no effect in interleukin-6 production after PH, but caused a delay in AP-1 and C/EBP binding and in the expression of c-jun and c-myc messenger RNA ( mRNA ) ... We conclude that TNFR-1, but not TNFR-2 , is necessary for liver regeneration, and that NF-kappaB and STAT3 binding are activated by signals transduced by TNFR-1