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ARSI — TNF
Text-mined interactions from Literome
Wang et al., Acta Pharmacol Sin 2002
:
1 ) In vivo, ASI 50-200 mg/kg ig for 7 d increased T lymphocyte proliferation and antibody production, and ASI 50-100 mg/kg ig for 7 d increased B lymphocyte proliferation but ASI 200 mg/kg had no effect on B lymphocyte proliferation ; 2 ) In vitro, ASI increased T, B lymphocyte proliferation only at 100 nmol/L ; 3 ) ASI increased IL-1 activity at 1 nmol/L in vitro, but decreased it at 100 and 1000 nmol/L ; 4 )
ASI inhibited
TNF-alpha activity with or without LPS-stimulation in vitro ...
ASI increased T, B lymphocyte proliferation and antibody production in vivo and in vitro ; but
inhibited productions of IL-1 and
TNF-alpha from peritoneal macrophages in vitro
Huang et al., Zhongguo Zhong Yao Za Zhi 2005
(Lung Neoplasms) :
To study the
effect of
Acanthopanax senticosus injection (ASI) on the activities of human
tumor necrosis factor (TNF) and natural killer cell ( NKC ) in the patients with lung cancer and the underlying mechanism