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ANG — IL8
Text-mined interactions from Literome
Pizurki et al., Br J Pharmacol 2003
:
4 In addition to its ability to inhibit PMN adherence,
Ang1 diminished
IL-8 production from EC challenged with thrombin in a concentration dependent manner
Inomata et al., Microbes Infect 2007
:
In addition,
angiopoietin (Ang)-2 , a substance of WPB,
enhanced IL-8 production by P. gingivalis LPS, suggesting that Ang-2 mediates the RgpA induced enhanced cell responses
Neagoe et al., J Cell Physiol 2012
:
Ang1 ( 10 ( -8 ) ?M ) induced a significant and maximal increase of IL-8 mRNA ( 4.7-fold ) within 1 h, and
promoted maximal
IL-8 protein synthesis ( 3.6-fold ) and release ( 5.5-fold ) within 2 h as compared to control PBS treated neutrophils ... Neutrophil pretreatment with a protein synthesis inhibitor ( CHX ) increased IL-8 mRNA synthesis by 18-fold, and reduced
Ang1 mediated
IL-8 protein synthesis and release by 96 % and 92 %, respectively
Gao et al., Ann Rheum Dis 2013
(Arthritis, Psoriatic...) :
Finally, DAPT significantly decreased
VEGF/Ang2 induced IL-6,
IL-8 , MMP2 and 9 expressions in RA synovial explants