Saavedra et al., Free Radic Biol Med 2005
:
Because exogenously applied GDNF prevented HO-1 up-regulation in cultures treated with H2O2 or l-DOPA, and antibody neutralization of GDNF prevented the secondary HO-1 down-regulation observed in neuron-glia cultures, we propose that GDNF negatively modulates HO-1 expression induced by oxidative stress
Hung et al., Mol Pharmacol 2008
(Parkinson Disease, Secondary) :
Overexpression of HO-1 increased the expression of BDNF and GDNF in astrocytes and BDNF in neurons
Guo et al., J Biomed Biotechnol 2010
:
We next analyzed the affinity of the ATF to the HMOX1 enhancer and the effect of the ATF on endogenous HMOX1 expression