Zhang et al., Mol Cell Biol 2006
:
Insulin induces multiprotein complex formation of RACK1 , IR, and STAT3
Qiu et al., Science signaling 2010
(Obesity, Morbid) :
RACK1 mediated the glucose-inducible assembly of a complex containing IRE1alpha, RACK1, and protein phosphatase 2A (PP2A) to promote dephosphorylation of IRE1alpha by PP2A, thereby inhibiting glucose stimulated IRE1alpha activation and attenuating IRE1alpha dependent increases in insulin production