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ERBB2 — PLXNB1

Pathways - manually collected, often from reviews:

• Reactome Reaction: ERBB2 → PLXNB1 (reaction) Swiercz et al., J Cell Biol 2004, Swiercz et al., J Biol Chem 2008*
• Reactome Reaction: ERBB2 → PLXNB1 (direct_complex)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Intact Interaction: ERBB2 — PLXNB1 (physical association, anti tag coimmunoprecipitation) Zhou et al., Molecular cancer 2012*

Text-mined interactions from Literome

Swiercz et al., J Cell Biol 2004 : Our data indicate that ErbB-2 is an important component of the plexin-B receptor system and that ErbB-2 mediated phosphorylation of plexin-B1 is critically involved in Sema4D induced RhoA activation, which underlies cellular phenomena downstream of plexin-B1, including axonal growth cone collapse
Worzfeld et al., J Clin Invest 2012 (Breast Neoplasms...) : Here we show that overexpression of ErbB-2 in human breast cancer cell lines leads to phosphorylation and activation of the semaphorin receptor Plexin-B1