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NTRK2 — SLC22A3
Text-mined interactions from Literome
Smit et al., Mol Cell Biol 2009
(Neoplasm Metastasis) :
This required
TrkB kinase activity, a functional mitogen activated protein kinase pathway, suppression of E-cadherin, and induction of Twist, a transcription factor
contributing to
EMT and metastasis
Kupferman et al., Oncogene 2010
(Carcinoma, Squamous Cell...) :
TrkB induces
EMT and has a key role in invasion of head and neck squamous cell carcinoma
Smit et al., Oncogene 2011
(Neoplasm Metastasis) :
We show here that Zeb1 is required for
TrkB induced
EMT in epithelial cells, as RNAi mediated knockdown of Zeb1 reverted the morphological changes induced by TrkB
Fujikawa et al., J Gastroenterol 2012
(Adenocarcinoma...) :
This study investigates whether TrkB expression is associated with the clinical outcome of colorectal cancer ( CRC ) patients and whether
TrkB induces
EMT in CRC cells ... These results indicate
TrkB could
induce EMT and play an important role in CRC progression to metastasis