Gene interactions and pathways from curated databases and text-mining

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CASP1 — SERP2

Text-mined interactions from Literome

MacNeill et al., Virology 2006 (Myxomatosis, Infectious) : SERP2-D294E prevented inhibition of caspase-8 , caspase-10 and granzyme-B ; and MYX-SERP2-D294E failed to block apoptosis in RK-13 cells, but was fully virulent in rabbits
Viswanathan et al., PloS one 2012 (Carotid Stenosis...) : With analysis in vitro of human cells in culture, Serp-2 selectively inhibited T cell caspase activity and blocked cytotoxic T cell ( CTL ) mediated killing of T lymphocytes ( termed fratricide )
Petit et al., J Virol 1996 : The biological relevance of this new serpin from MV was monitored, and it was shown that Serp2 could inhibit human interleukin-1 beta converting enzyme activity
Messud-Petit et al., J Virol 1998 (Myxomatosis, Infectious) : Serp2 , an inhibitor of the interleukin-1beta converting enzyme , is critical in the pathobiology of myxoma virus