UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

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ATP2A2 — ATP5O

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

IRef Intact Interaction: Complex of 244 proteins (association, pull down) Komarova et al., Mol Cell Proteomics 2011
IRef Intact Interaction: Complex of 306 proteins (association, pull down) Komarova et al., Mol Cell Proteomics 2011
IRef Intact Interaction: Complex of 156 proteins (association, anti tag coimmunoprecipitation) Lau et al., Cell 2012

Text-mined interactions from Literome

Miyamoto et al., Proc Natl Acad Sci U S A 2000 (Heart Failure...) : Overexpression of SERCA2a restored both SERCA2a expression and ATPase activity to nonfailing levels
Khan et al., Heart Fail Rev 2009 (Acute Disease...) : Istaroxime, a first in class new chemical entity exhibiting SERCA-2 activation and Na-K-ATPase inhibition : a new promising treatment for acute heart failure syndromes ?