Gene interactions and pathways from curated databases and text-mining

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DAPK3 — MYO10

Text-mined interactions from Literome

Niiro et al., J Biol Chem 2001 : These results suggest that ZIP kinase is responsible for Ca ( 2+ ) independent myosin phosphorylation and contraction in smooth muscle
Komatsu et al., J Cell Biol 2004 : The kinase responsible for the phosphorylation was ZIP kinase because ( a ) the kinase in the cell extracts phosphorylated Ser19 and Thr18 of MLC20 with similar potency ; ( b ) immunodepletion of ZIP kinase from the cell extracts markedly diminished its myosin II kinase activity ; and ( c ) disruption of ZIP kinase expression by RNA interference diminished myosin phosphorylation, and resulted in the defect of cell polarity and migration efficiency ... These results suggest that ZIP kinase is critical for myosin phosphorylation and necessary for cell motile processes in mammalian fibroblasts