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IRF1 — IRF9
Pathways - manually collected, often from reviews:
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Xi et al., Oncogene 1999
(Pancreatic Neoplasms) :
Here we report that the human CIITA Type IV promoter
IRF-E binds IRF-1 and can be
activated by exogenous expression of
IRF-1
Xi et al., Mol Immunol 2003
:
Off-rate experiments revealed that the
IRF-2/IRF-E complex was more stable than the IRF-1/IRF-E complex and that the affinity of
IRF-1 for the IRF-E was
increased when IRF-1 co-occupied the IRF-E with IRF-2
Guo et al., J Immunol 2005
:
IRF-2 constitutively binds to the two ISRE/IRF-E sites at the DRR, while
IRF-1 and STAT1 are
induced to bind to the two
ISRE/IRF-E sites and the ISRE/IRF-E1, respectively, only after IFN-beta treatment
Pan et al., Zhongguo Shi Yan Xue Ye Xue Za Zhi 2010
(Leukemia, Promyelocytic, Acute) :
It is concluded that during ATRA induced APL cell differentiation,
IRF-1 is first upregulated by ATRA, and then
IRF-1 increases the protein levels of IRF-9 and STAT2 with the downregulation of C/EBPalpha
Lou et al., Exp Cell Res 2011
:
In addition, we also found that
IRF-1 could
regulate RIG-G induction as well as the expression of
IRF-9 and STAT2 in some cases
Kondo et al., Hokkaido Igaku Zasshi 1996
(Leukemia...) :
Functional analysis showed that
IRF-BP inhibited DNA binding and transcriptional activity of
IRF-1