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NOS1 — SOD1
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
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Gene Ontology Complexes protein complex:
protein complex complex (HSF1-TRMT112-HIST1H4A-UBQLN1-CDX2-USP28-HDAC5-CAV3-CANX-LHX1-TUBA3C-TUBA3E-PI4K2A-NR0B2-RYR2-NTRK1-MPP5-N6AMT1-STAP1-ZFP42-FADD-ATP6V0D1-PRKCDBP-AQP2-FNTB-PRPSAP2-WIPI2-CRB3-CRB2-PEX11A-LDB1-RBP4-TMEM102-GATA2-ADCY2-DZIP1-SYK-TUBB4B-PTPN11-KAT5-CEP290-SYP-ASF1B-PLEKHA2-KIF24-MYO5B-RGP1-CFTR-SPTBN5-VPS72-ACTA2-PRKCI-CNST-SNX4-GNAO1-NFKBIA-UBE2D2-EPB41-RAB5A-GLUL-BSND-GSK3B-SKI-XRCC6-PPM1E-TTR-TUBA1A-SUCLG1-TRIAP1-AKT1S1-MYD88-NPPB-GDF11-INCENP-PLCB3-BECN1-PRKAB1-SOD1-TUBB1-NPHS2-NPHS1-EPS8L1-GDI1-TUBB2A-TUBB2B-SUCLG2-PEX3-TUBAL3-ERLIN1-MAGED1-GCH1-TUBB-CPS1-MEF2C-ZNF703-SLC22A6-CPLX1-EIF4EBP1-TUBE1-FLNA-CD19-STX1A-HDAC2-TOMM40L-HDAC6-SMAD6-SMAD7-TLE6-SMAD2-PARD6B-STXBP1-ACR-TRPC1-PARD6A-TRPC4-PANX1-DCTN1-SOX9-PXMP2-BCR-SET-MALT1-BHMT-RILP-TRADD-HIST1H3A-MAPK1-PVALB-NFKB1-NUFIP1-ACVR2B-TAL1-FOXP3-SSX2IP-GNB2-SLC27A5-GOPC-PAX2-CXADR-AIF1L-APBA1-MYL12A-LMO2-ID2-CCDC113-DDOST-SPP2-GATAD2B-PLN-ERCC8-BIRC8-ASF1A-CAB39-BIRC3-BIRC2-CTNNB1-CORO1A-PRELID1-HAND2-CHAF1B-SCAP-GNAT3-CDC20-SMARCA4-IQGAP1-YWHAZ-CEBPA-PRPS2-AXIN1-XRCC5-YWHAQ-UVRAG-SLC51B-RGS4-RGS6-HTT-YWHAB-APCS-CDCA8-RIPK1-MTA2-SIN3A-ANXA1-NOS1-SNTA1-TRAF6-KPNB1-VCL-VCP-PTRF-PRKCZ-SKIL-RAB3A-KRIT1-SSBP3-PRPSAP1-PPP1CC-TAB1-MYO6-ACTL7A-TUBG2-MBD2-COL6A1-COL6A2-BCL3)
Helps et al., Biochem J 2000, Lauderdale et al., Proc Natl Acad Sci U S A 2000, Didichenko et al., FEBS Lett 2000, Koh et al., Curr Biol 2002, Fan et al., Mol Cell Biol 2002, Groisman et al., Cell 2003, Offenhäuser et al., Mol Biol Cell 2004, Tagami et al., Cell 2004, Doyon et al., Mol Cell Biol 2004, Moore et al., Genomics 2004, Sun et al., Mol Cell 2004, Zang et al., J Cell Biochem 2004, Tian et al., Cancer Res 2005, An et al., Biochemistry 2005, Mahajan et al., Proc Natl Acad Sci U S A 2005, Vader et al., EMBO Rep 2006, Yeh et al., J Biol Chem 2006, Li et al., Immunol Rev 2006, Agbas et al., Biochem J 2007, Swiatecka-Urban et al., J Biol Chem 2007, McKeegan et al., Mol Cell Biol 2007, Shono et al., J Am Soc Nephrol 2007, Popov et al., Cell cycle (Georgetown, Tex.) 2007, Sato et al., J Biol Chem 2008, Fitzgerald et al., J Biol Chem 2008, Lyssand et al., J Biol Chem 2008, Figaro et al., FEBS Lett 2008, Ueda et al., Proc Natl Acad Sci U S A 2008, Shimojo et al., J Biol Chem 2008, Costantini et al., Blood 2009, Mitsuishi et al., J Biol Chem 2010, Masuda et al., J Biol Chem 2010, Koch et al., J Cell Sci 2010, Boëda et al., J Biol Chem 2011, Sircoulomb et al., EMBO Mol Med 2011, Hoxhaj et al., J Cell Sci 2012, Uckun et al., Proc Natl Acad Sci U S A 2012, Pusapati et al., J Biol Chem 2012, Ghai et al., Proc Natl Acad Sci U S A 2013, Kelly et al., PLoS Biol 2013, Chiang et al., PloS one 2013, Dauphinee et al., J Immunol 2013, Potting et al., Cell Metab 2013, Ludwig et al., PLoS Biol 2013, Lee et al., Proc Natl Acad Sci U S A 2013, Kobayashi et al., J Cell Biol 2014, Zheng et al., Am J Physiol 1994, Kumar et al., Biochem Biophys Res Commun 1998, Watabe-Uchida et al., J Cell Biol 1998, Haft et al., Mol Cell Biol 1998
Text-mined interactions from Literome
Didier et al., FASEB J 1999
:
Cells were also treated either with L-thiocitrulline ( L-Thio ), an irreversible
inhibitor of
NOS , or with exogenous
superoxide dismutase ( SOD ) and catalase
González et al., Braz J Med Biol Res 2000
(Diabetes Mellitus, Experimental) :
Moreover, inhibition of
NOS activity produces an
increase in
SOD activity and a decrease in lipoperoxidation in diabetic pancreatic tissues
Vouldoukis et al., Mol Med 2000
:
The concomitant stimulation of the FcyR and the translocation of the
SOD1 in the cytoplasm of IFN-gamma activated macrophages not only reduced the production of superoxide anion but also
induced the expression of the inducible form of
nitric oxide synthase ( iNOS ) and the related NO production
Hu et al., Acta Pharmacol Sin 2001
(Disease Models, Animal...) :
In the rat peritonitis induced by carrageenan, rh-bFGF 4 kU/kg decreased the MDA and NO levels,
inhibited the
NOS activity, augmented the
SOD activity, and lowered the production of PGE ( 2 ) in exudate
Kawahara et al., Free radical research 2002
(Glioma...) :
This increased resistance to NO toxicity in differentiated cells was almost completely cancelled out by inhibiting the activity of
superoxide dismutase ( SOD ) , but not by
inhibiting the activity of
NOS
Hu et al., Zhongguo Zhong Xi Yi Jie He Za Zhi 2007
(Brain Ischemia...) :
After being treated with the combination of both TA, the average neurological score, cerebral infracted volume, cerebral water content, activity of
NOS and content of MDA in the model rats significantly decreased, and the activity of
SOD was significantly
increased ( all P < 0.05 )
Baldelli et al., Int J Biochem Cell Biol 2008
:
nNOS increase also
mediates a down-regulation of copper, zinc
superoxide dismutase ( SOD1 ) in terms of mRNA production, protein and activity levels ... The
nNOS inhibitor ( 7-Ni ), while restores the GSH content, does not
recover the
SOD1 level, suggesting that NO is not directly involved in SOD1 modulation
Lee et al., Exp Mol Med 2009
:
Differential
regulation of inducible
nitric oxide synthase and cyclooxygenase-2 expression by
superoxide dismutase in lipopolysaccharide stimulated RAW 264.7 cells
Liu et al., Brain Res 2012
(Disease Models, Animal...) :
The results showed that after PFC administration, the latency to first electrical discharge in EEG was significantly shortened ; MDA, H ( 2 ) O ( 2 ), NO levels and
NOS activity
increased ; and
SOD , GPx and CAT activities decreased
Berman et al., Br J Pharmacol 1993
:
3. The increase in albumin transfer induced by hypoxanthine and xanthine oxidase was abolished by catalase ( 3 u ml-1 ), reduced by allopurinol ( 4 mM ), but unaffected by
superoxide dismutase ( 6000 u ml-1 ), the hydroxyl radical scavengers, mannitol ( 15 mM ), dimethylthiourea ( 10 mM ) and N- ( 2-mercaptopropionyl ) -glycine ( 1 mM ), the iron chelator, deferoxamine ( 0.5 mM ), ferric chloride ( 50 microM ), an
inhibitor of
nitric oxide synthase , NG-nitro-L-arginine ( 30 microM ), or the antioxidant, dithiothreitol ( 3 mM )
Allen et al., J Infect Dis 1997
:
The possibility that peroxynitrite contributes to this maximum luminol dependent activity was tested, but neither
superoxide dismutase , a competitive inhibitor of peroxynitrite production, nor N-methyl-L-arginine, an
inhibitor of
nitric oxide synthase , exerted a significant inhibitory effect
Nelson et al., Hum Reprod 1998
:
In both P and NP arteries the cholinergic relaxation was increased in the presence of
superoxide dismutase and greatly
reduced in the presence of the
nitric oxide synthase inhibitors, NG-mono-methyl L-arginine ( L-NMMA ) and L-nitro-arginine-methylester ( L-NAME )