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BMP4 — PITX2

Text-mined interactions from Literome

St Amand et al., Dev Biol 2000 : It thus appears that the early expression patterns of Pitx1 and Pitx2 in the developing mandible are regulated by the antagonistic effects of FGF8 and BMP4 such that the Pitx1 and Pitx2 expression patterns are defined
Liu et al., Development 2003 (Abnormalities, Multiple...) : Analysis of Pitx2 allelic combinations that encode varying levels of Pitx2 showed that repression of Bmp signaling requires high Pitx2 while maintenance of Fgf8 signaling requires only low Pitx2