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CDKN1A — IL24

Text-mined interactions from Literome

Muroya et al., Oncogene 1992 : In contrast, basic fibroblast growth factor, interleukin 6 and dibutyryl cAMP, which induce neuronal differentiation of PC12 cells, did not stimulate the accumulation of p21-GTP at any time point examined
Kokkinakis et al., Cancer Lett 2006 (Neoplasms) : The response of tumors to MET-stress depends on their mutational status, however, it always involves inhibition of CDK1 and in most cases the upregulation of p21 , p27, GADDs and 14-3-3sigma in response to upregulation of TGF-beta, IRF-1, TNF-alpha, Rb and/or MDA-7 and the downregulation of PI3K, RAS and NF-kappaB ... Although inhibition of the cell cycle and mitosis is not necessarily dependent on the tumor 's p53 status, the expression of p21 , GADD45 and apoptosis related genes ( BAX, BCL-2 ) are regulated by wt-p53, in addition to their regulation by TGF-beta or MDA-7 in mutated p53 tumors
Zhang et al., Curr Cancer Drug Targets 2013 (Lung Neoplasms...) : Additionally, MSCs mediated IL24 expression led to an increase in the cleavage of caspases-3/8/9 and PARP, the Bax/Bcl-2 ratio, as well as the p21 expression in A549 cells