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IL13 — TGFB2
Text-mined interactions from Literome
Lee et al., J Exp Med 2001
(Pulmonary Fibrosis) :
We hypothesized that the fibrogenic effects of
IL-13 are
mediated by
transforming growth factor ( TGF ) -beta
Wen et al., Am J Respir Cell Mol Biol 2002
:
IFN-gamma reduced both basal, IL-4-, and
IL-13 stimulated release of
TGF-beta2 in human bronchial epithelial cells
Bry et al., Am J Obstet Gynecol 1992
(Obstetric Labor, Premature) :
Human amnion cells in monolayer culture were treated with
interleukin-1 , tumor necrosis factor, or vehicle in the
presence or absence of
transforming growth factor-beta
Finotto et al., Int Immunol 2005
(Asthma) :
IL-13 blockade also
led to reduced eosinophilia and decreased vimentin,
transforming growth factor beta ( TGF-beta ) and alpha smooth muscle actin ( alphaSMA ) levels
Roberts et al., Mol Hum Reprod 2005
:
We also showed that tumour necrosis factor-alpha ( TNF-alpha ; 10 and 25 ng/ml ) and
transforming growth factor-beta ( TGF-beta; 1 and 5 ng/ml ), cytokines with inflammatory and immune regulatory functions in a cell- and dose dependent manner
regulate the expression of
IL-13 and IL-15 ( P < 0.05 )
Malavia et al., Respir Res 2008
(Pulmonary Fibrosis) :
IL-13 induced increasing levels of MUC5AC protein, and
TGF-beta2 , while decreasing beta-Tubulin IV at day 22 and 28 in the NHBE
Layh-Schmitt et al., Curr Opin Rheumatol 2008
(Spondylarthropathies) :
In mice,
transforming growth factor-beta and interleukin-6 are critical, whereas interleukin-23 is more important at later stages
promoting interleukin-17 production
Shimamura et al., Clin Cancer Res 2010
(Adenocarcinoma...) :
IL-13 causes
transforming growth factor-beta activation via AP-1 pathway, which may cause tumor induced immunosuppression in the host
Marth et al., Eur J Immunol 1997
:
Regulation of
transforming growth factor-beta production by
interleukin-12
Fulton et al., J Infect Dis 1998
:
Regulation of
interleukin-12 by interleukin-10,
transforming growth factor-beta , tumor necrosis factor-alpha, and interferon-gamma in human monocytes infected with Mycobacterium tuberculosis H37Ra