Gene interactions and pathways from curated databases and text-mining

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GRAP2 — MAPKAPK2

Text-mined interactions from Literome

Platanias et al., Pharmacol Ther 2003 (Leukemia, Myelogenous, Chronic, BCR-ABL Positive) : The activated form of p38 regulates downstream activation of other serine kinases, notably MapKapK-2 and MapKapK-3, indicating the existence of Type I IFN dependent signaling cascades activated downstream of p38
Hu et al., J Biol Chem 2006 (MAP Kinase Signaling System) : MAPKAPK-2 , Akt2, and ezrin phosphorylation were all attenuated by p38 MAPK inhibition but were unaffected by dominant negative ezrin expression
Gorog et al., Cell Stress Chaperones 2009 (Myocardial Ischemia) : p38-MAPK activation is thought to contribute to myocardial ischemic injury ; therefore, we investigated MK2 effects on ischemic injury and p38 cellular localization using MK2-deficient mice ( KO )
Hendriks et al., BMC systems biology 2010 : We found that in a dual ( MK2 and ATF2 ) substrate assay, MK2-p38 interaction reduced the activity of p38 against ATF2
Marshall et al., J Immunol 1998 : IL-4 induced a late ( > 4-h ) increase in p38 MAPK activity and corresponding activation of its substrate MAPKAPK-2