◀ Back to CCR4

CCR4 — FOSL2

Text-mined interactions from Literome

Nakayama et al., Oncogene 2008 (Leukemia-Lymphoma, Adult T-Cell) : Consistently, the Fra-2/JunB and Fra-2/JunD heterodimers strongly activated the CCR4 promoter in Jurkat cells ... Collectively, aberrantly expressed Fra-2 in association with JunD may play a major role in CCR4 expression and oncogenesis in ATL
Yoshie et al., Uirusu 2008 (Leukemia-Lymphoma, Adult T-Cell) : We have also shown that ATL cells aberrantly express the AP-1 family member Fra-2 which, by forming the heterodimer with JunD, potently induces the expression of not only CCR4 but also the genes such as c-Myb, MDM2 and Bcl-6, the well-known proto-oncogenes