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IL13 — PPARG
Text-mined interactions from Literome
Berry et al., Eur J Immunol 2007
:
IL-13 induces expression of CD36 in human monocytes through
PPARgamma activation ... These results reveal a novel
role for
PPARgamma in the alternative activation of monocytes by
IL-13 , suggesting that endogenous PPARgamma ligands, produced by phospholipase A2 activation, could contribute to the biochemical and cellular functions of CD36
Dubourdeau et al., Eur Cytokine Netw 2008
:
Since
IL-13 signalisation
involves PPARgamma , we tested PPARgamma involvement in p21WAF1 gene activation by using metabolic inhibitors of arachidonic acid metabolism, or by restoring PPARgamma expression in a defective cell line