Gene interactions and pathways from curated databases and text-mining

◀ Back to ATP5O

ATP5O — EDN1

Text-mined interactions from Literome

Vaziri et al., J Hypertens Suppl 2002 (Hypertension) : Several mechanisms have been shown to contribute to the pathogenesis of lead induced hypertension : ( 1 ) avid oxidation and inactivation of endogenous nitric oxide ( NO ) by reactive oxygen species leading to functional NO deficiency ; ( 2 ) increased sympathetic activity and circulating noradrenaline coupled with decreased vascular and elevated renal beta-adrenergic receptor density ; ( 3 ) increased angiotensin converting enzyme (ACE) activity and elevated plasma renin, angiotensin II and aldosterone levels ; ( 4 ) heightened kininase I and kininase II activities ; ( 5 ) possible increase in endothelin and thromboxane production ; and ( 6 ) lead mediated inhibition of vascular smooth muscle Na ( + ) -K+ ATPase leading to a rise in cellular Na+ and hence Ca2+ stores
Krishnamoorthy et al., J Ocul Pharmacol Ther 2003 : Regulation of Na, K-ATPase expression by endothelin-1 in transformed human ciliary non pigmented epithelial ( HNPE ) cells
Garvin et al., J Am Soc Nephrol 1991 : The effects of endothelin on fluid and bicarbonate absorption and Na+/K+ ATPase activity in the proximal straight tubule were investigated
Meyer-Lehnert et al., Biochem Biophys Res Commun 1989 : Therefore, we examined the effects of endothelin on Na-K-ATPase in an enzyme preparation from hog cerebral cortex ... At high concentrations, endothelin ( 10 ( -5 ) M ) inhibited Na-K-ATPase in vitro
Kawai et al., J Neurochem 1995 : Endothelin 1 stimulates Na+, K ( + ) -ATPase and Na ( + ) -K ( + ) -Cl- cotransport through ETA receptors and protein kinase C-dependent pathway in cerebral capillary endothelium
McClellan et al., Circ Res 1996 : Effect of endothelin-1 on actomyosin ATPase activity ... From 1 to 50 pmol/L endothelin-1 did not alter force development in isolated trabeculae with intact endothelial cells, but actomyosin ATPase activity was increased