Gentile et al., Proc Natl Acad Sci U S A 2006
(Ion Channel Gating) :
PP5 stimulation by Rac provides a unique molecular mechanism for the antagonism of Rho dependent signaling through protein kinases in many cellular processes, including metastasis, immune cell chemotaxis, and neuronal development
Chatterjee et al., J Biol Chem 2010
:
Consequently, activation of Rac1 promoted PP5 translocation to the plasma membrane in intact cells and stimulated PP5 phosphatase activity in vitro