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CD40 — LEP
Text-mined interactions from Literome
Gultekin et al., World J Gastroenterol 2007
(Acute Disease...) :
Exogenous
leptin attenuates inflamma-tory changes, and
reduces pro-inflammatory cytokines, nitric oxide levels, and
CD40 expression in cerulein induced AP and may be protective in AP associated ALI
Lam et al., J Biol Chem 2007
:
Leptin induces
CD40 expression through the activation of Akt in murine dendritic cells ... In this study, we showed that
leptin induced
CD40 expression in murine DC and significantly up-regulated their immunostimulatory function in driving T cell proliferation ... Thus, our results have elucidated the molecular mechanisms underlying
leptin induced
CD40 expression and DC maturation