Gene interactions and pathways from curated databases and text-mining

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CRK — PHKA2

Text-mined interactions from Literome

Blaukat et al., J Biol Chem 1999 : Pyk2 induced activation of Src is necessary for phosphorylation of Shc and p130Cas and their association with Grb2 and Crk , respectively, and for the activation of ERK and JNK cascades
Yi et al., J Neurovirol 2004 (AIDS Dementia Complex) : The authors also showed that both R5 and X4 gp120 activate intracellular signals in macrophages through CCR5 and CXCR4, including calcium elevations ; K+, Cl- and nonselective cation channel activation ; phosphorylation of the nonreceptor tyrosine kinase Pyk2 ; and activation of p38 and SAPK/JNK mitogen activated protein kinases ( MAPKs )