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CRK — PHKA2
Text-mined interactions from Literome
Blaukat et al., J Biol Chem 1999
:
Pyk2 induced activation of Src is
necessary for phosphorylation of Shc and p130Cas and their association with Grb2 and
Crk , respectively, and for the activation of ERK and JNK cascades
Yi et al., J Neurovirol 2004
(AIDS Dementia Complex) :
The authors also showed that both R5 and X4 gp120 activate intracellular signals in macrophages through CCR5 and CXCR4, including calcium elevations ; K+, Cl- and nonselective cation channel activation ; phosphorylation of the nonreceptor tyrosine kinase
Pyk2 ; and
activation of
p38 and SAPK/JNK mitogen activated protein kinases ( MAPKs )