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NGF — VGF

Text-mined interactions from Literome

Hawley et al., J Neurosci 1992 : NGF induces the expression of the VGF gene through a cAMP response element
Baybis et al., FEBS Lett 1992 : In this communication we show that NGF-treatment for 60-90 min maximally increases VGF gene transcription by 12- to 14-fold
van den Pol et al., J Comp Neurol 1994 : The lack of colocalization of VGF and nerve growth factor receptor suggests that, unlike expression in PC12 cells, VGF expression in neurons from the central nervous system does not require nerve growth factor stimulation
Salton et al., FEBS Lett 1995 : Maximal inhibition of VGF mRNA induction was achieved using K-252a, an inhibitor of the NGF-receptor Trk tyrosine kinase, and by mutating both Y490 ( SHC association site ) and Y785 ( PLC-gamma 1 association site ) of Trk. Inhibitors of the NGF activated protein kinase N ( PKN ) were found to partially and in some cases transiently block VGF induction by NGF while in PKA-deficient PC12 cells, VGF induction by NGF was comparable to that observed in parental PC12 cells
Miyatake et al., Biochem Mol Biol Int 1993 : 2 ) The induction of VGF protein by NGF was inhibited by methylthioadenosine ( MTA ), but its induction by bFGF was not ... 3 ) The induction of VGF protein by NGF was blocked by staurosporine, but its induction by bFGF was not ... These findings suggest that the induction of VGF by NGF is distinct from that by bFGF in terms of sensitivities to MTA and staurosporine
Luc et al., J Mol Neurosci 1997 : We have begun to analyze the mechanism by which NGF induces the expression of a neural specific gene, VGF , in PC12 cells