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BCR — CDK6
Text-mined interactions from Literome
Tanguay et al., J Immunol 1999
:
These results suggest that assembly or stabilization of D-type cyclin holoenzyme complexes 1 ) is an important step in the
activation of
Cdk4/6 by
BCR signals, and 2 ) suffice in providing a mechanism to account for inhibition of BCR stimulated Rb protein phosphorylation by Fc gamma R
Cortez et al., Oncogene 1997
:
Here we show that
Bcr-Abl signaling
prevents down-regulation of
cyclin dependent kinase activity and cell cycle arrest after growth factor deprivation of hematopoietic progenitor cells