McKay et al., Mol Endocrinol 2000
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GR-mediated repression of p65 transactivation and p65 mediated repression of GR transactivation, as well as the physical interaction between NF-kappaB and GR, are enhanced by CBP ... However, CBP does not physically interact with antagonist bound GR and does not enhance its repressive effect on p65 Pyo et al., Biochem Biophys Res Commun 2008
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CBP/p300 induced hyperacetylation as well as phosphorylation of p65 was implicated in ROS mediated LTR activation