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CCL3 — FGFR3
Text-mined interactions from Literome
Masih-Khan et al., Blood 2006
(Bone Diseases...) :
Down-regulation of
MIP-1 alpha was not, however,
observed following
FGFR3 inhibition in MM cells with RAS mutations implicating RAS-MAPK in MIP-1 alpha regulation
Waldburger et al., Arthritis Rheum 2008
(Arthritis, Rheumatoid...) :
ACh significantly
reduced the production of IL-6, CXCL8, CCL2,
CCL3 , CCL5, and granulocyte colony stimulating factor by IL-1 stimulated FLS
Krejci et al., J Biol Chem 2010
(Multiple Myeloma...) :
Similarly, NF449 antagonized FGFR3 action in the multiple myeloma cell lines OPM2 and KMS11, as evidenced by NF449 mediated reversal of ERK MAPK activation and transcript accumulation of
CCL3 and CCL4 chemokines, both of which are
induced by
FGFR3 activation