Somvanshi et al., Int J Cardiol 2013
(Cardiomegaly) :
SST enhances ß2AR agonist formoterol mediated effects on PKA , CREB and ERK1/2 phosphorylations whereas it inhibits isoproterenol mediated ERK1/2 and p38 signaling in concentration dependent manner
Bullock et al., Biochemistry 1998
:
Fluorescent electrophoretic mobility shift assays show that phosphorylation by PKA results in a 3-5-fold increase in the binding affinity of CREB to both the symmetrical somatostatin CRE (SMS-CRE) and the asymmetric somatostatin upstream element (SMS-UE)