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ATP5O — UPF2
Text-mined interactions from Literome
Chamieh et al., Nature structural & molecular biology 2008
:
In the UPF trimeric complex,
UPF2 and UPF3b cooperatively
stimulate both
ATPase and RNA helicase activities of UPF1
Stalder et al., RNA 2009
:
However, the accumulation of the
ATPase-deficient UPF1 mutant in P-bodies is
independent of
UPF2 , UPF3b, or SMG1, and the ATPase-deficient UPF1 mutant can localize into the P-bodies independent of its phosphorylation status
Chakrabarti et al., Mol Cell 2011
:
The essential RNA dependent
ATPase activity of Upf1 is
triggered by the formation of the surveillance complex with
Upf2-Upf3
Carroll et al., J Cell Biol 2011
:
Whereas Dhh1 's
ATPase activity was not
required to induce translational inhibition and
mRNA decay when directly tethered to an mRNA, ATP hydrolysis regulated processing body dynamics and the release of Dhh1 from these RNA-protein granules