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GP2 — HDAC2
Text-mined interactions from Literome
Singh et al., Scand J Immunol 2001
(Acute-Phase Reaction) :
Both in vivo and in vitro the maximum production of CSFs occurred 6 h after initiation of stimulation, and returned to the background levels by 48 h. Mannose 6-P, mannose 1-P and mannose, and not other sugars inhibited the SAP induced production of CSFs by macrophages which suggests that
SAP interaction with macrophages was
mediated by specific
glycoprotein-receptors
Castro-Galache et al., Int J Cancer 2003
:
Thus, reverse transcription-PCR and Western immunoblots confirm that both
histone deacetylase inhibitors
promote endogenous down-regulation of
P-glycoprotein , which is overexpressed in the drug-resistant cells ... Transfection of drug-sensitive cells with the P-glycoprotein cDNA ruled out the a priori possible association between apoptosis and down-regulation of
P-glycoprotein induced by the
histone deacetylase inhibitors
Barnes et al., Lancet 2009
(Asthma...) :
Some examples of this approach are inhibition of p38 MAP kinase, use of vitamin D to restore interleukin-10 response,
activation of
HDAC2 expression by use of theophylline, antioxidants, or phosphoinositide-3-kinase-delta inhibitors, and inhibition of macrophage migration inhibitory factor and
P-glycoprotein