Gene interactions and pathways from curated databases and text-mining

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RPS27L — TP53

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Li et al., Cancer Res 2007 (Genomic Instability) : Through this mechanism, RPS27L induction by p53 facilitates p21 mediated cell cycle arrest and protects against DNA damage induced apoptosis
Xiong et al., Oncogene 2011 : Ectopic expression of RPS27L or RPS27 inhibits MDM-2 mediated p53 ubiquitination and increases p53 levels by extending p53 protein half-life, whereas siRNA silencing of RPS27L decreases p53 levels by shortening p53 half-life, with a corresponding reduction in p53 transcription activity