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HTR2C — PRL

Text-mined interactions from Literome

Meltzer et al., Biol Psychiatry 1995 : Previous reports based on studies with serotonin ( 5-HT ) precursors or direct acting agonists have suggested that postsynaptic 5-HT1A and 5-HT2A/5-HT2C receptors may stimulate cortisol and prolactin (PRL) secretion in man ... These data suggest that the MK-212 induced cortisol response may be mediated by 5-HT2A or 5-HT2C receptor activation, or both, despite 5-HT1A inhibition ; however, PRL secretion by MK-212 requires 5-HT1A receptor availability as well as 5-HT2A/5-HT2C receptor activation, since blockade of the former appears to blunt the PRL responses to MK-212
Meltzer et al., Psychopharmacologia 1994 : Previous studies with direct acting serotonin ( 5-HT ) agonists and antagonists have demonstrated that stimulation of 5-HT1A, 5-HT1C and 5-HT2 receptors may promote cortisol and prolactin (PRL) secretion in man ... There is also evidence that 5-HT1C/2 receptor stimulation contributes to the cortisol and PRL responses following administration of the 5-HT precursor, L-5-hydroxytryptophan ( L-5-HTP ), in man
Goodall et al., Psychopharmacologia 1993 : The results suggest that 5-HT2 or 5-HT1C receptors mediate the effects of d-fenfluramine on appetite, prolactin secretion and temperature in humans
Aulakh et al., J Pharmacol Exp Ther 1994 : These findings demonstrate involvement of 5-HT2A/5-HT2C and 5-HT3 receptors in mediating DOM induced increases in plasma prolactin , whereas DOM induced increases in ACTH appear to be mediated by stimulation of 5-HT2A receptors
Albinsson et al., Eur J Pharmacol 1994 : The present study examined the involvement of 5-HT1C and 5-HT2 receptors in the regulation of prolactin release in the rat
Meltzer et al., Psychiatry Res 1995 : To examine further the role of 5-HT1A and 5-HT2A/5-HT2C receptors in prolactin and cortisol secretion in healthy men, the effects of meta-chlorophenylpiperazine ( mCPP ), a potent 5-HT receptor agonist, on the above hormones were studied in eight healthy men with and without pindolol pretreatment
Bagdy et al., Behav Brain Res 1996 : Role of the hypothalamic paraventricular nucleus in 5-HT1A, 5-HT2A and 5-HT2C receptor mediated oxytocin, prolactin and ACTH/corticosterone responses