Gene interactions and pathways from curated databases and text-mining

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HMGCR — RAC1

Text-mined interactions from Literome

Whaley-Connell et al., Am J Nephrol 2007 (Albuminuria...) : To investigate the role of HMG-CoA reductase inhibition of Rac1 and oxidative stress we used the opossum kidney PTC
Singh et al., Blood 2011 (Ischemia) : Simvastatin, a potent inhibitor of HMG-CoA reductase , suppressed 15 ( S ) -HETE induced Rac1 activation in HDMVECs affecting their migration and tube formation