Subbaiah et al., Atherosclerosis 1985
:
Modification of the arginine groups of LDL reversibly inhibited the activation of LAT Subbaiah et al., Metabolism 1982
(Abetalipoproteinemia) :
The LAT activity of normal plasma was only stimulated by two-threefold by LDL Ezaki et al., Biochim Biophys Acta 1994
:
Stimulation of EC with either thrombin ( 0.01-1 U/ml ) or Ca ( 2+ ) -ionophore A23187 ( 10 ( -10 ) -10 ( -7 ) M ) dose- and time-dependently enhanced LAT activity in the presence of LDL ( 1 mg protein/ml ), but no enhancement was observed in quiescent cells ... These results suggest that the transport of LDL into EC is facilitated by stimulation with thrombin and other agonists, and LDL subsequently activates intracellular LAT Liu et al., Biochim Biophys Acta 1993
:
The lysolecithin acyltransferase (LAT) activity of lecithin-cholesterol acyltransferase ( LCAT ) converts lysophosphatidylcholine ( lyso PC ) to PC, and requires low-density lipoproteins (LDL)