UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

◀ Back to PIK3CB

JAK1 — PIK3CB

Pathways - manually collected, often from reviews:

KEGG Jak-STAT signaling pathway: JAK1/JAK2/JAK3/TYK2 → PIK3CA/PIK3CB/PIK3CD/PIK3CG/PIK3R1/PIK3R2/PIK3R3/PIK3R5 (protein-protein, phosphorylation)
Reactome Reaction: JAK1 → PIK3CB (indirect_complex)
Reactome Reaction: JAK1 → PIK3CB (reaction) Wickrema et al., J Biol Chem 1999, Gu et al., Mol Cell 1998
WikiPathways Focal Adhesion-PI3K-Akt-mTOR-signaling pathway: JAK3/JAK2/JAK1 → PIK3CA/PIK3R1/PIK3IP1/PIK3R2/PIK3CB/PIK3CD/PIK3R4 (activation)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

STRING interaction: PIK3CB — JAK1 (interaction, mapped from grid kegg_pathways)
STRING interaction: JAK1 — PIK3CB (interaction, mapped from bind)