Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
MAPK14
→
P2RX5
(increases, P2RX5 Activity, MAPK14 Activity)
Evidence: P2RX5 activation results in a rapid and transient flow of cations across the plasma membrane recent research on P2RX7 demonstrates that ionotropic receptors interact with cytoskeletal and signaling proteins and can produce long-term effects on cellular activity the results presented in this paper suggest that activation of the P2RX5 receptor can produce changes in MAPK signaling pathways by analogous mechanisms