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PPARG — TP53

Pathways - manually collected, often from reviews:

• FastForward regulation: NFKB1, PPARG → TP53 (transcriptional regulation, increase) Bonofiglio et al., Mol Endocrinol 2006*
  Evidence: DNABINDING

Text-mined interactions from Literome

Okura et al., Eur J Pharmacol 2000 : These results strongly suggest that troglitazone can induce vascular smooth muscle cell apoptosis and that this effect is caused primarily by activation of the p53 and Gadd45 pathway but not by PPARgamma activation
Zand et al., Mol Cell Biochem 2007 : Interestingly, DHA was found to induce the expression of p53 protein in Reh cells in a PPAR-gamma dependent manner